Palmitoyl chloride → 5'-O-palmitoyldeoxycytidine

HRID 378822

반응식

HRID 378822 반응식
Cl.[C@@H:2]1([N:10]2[CH:17]=[CH:16][C:14]([NH2:15])=[N:13][C:11]2=[O:12])[O:9][C@H:6]([CH2:7][OH:8])[C@@H:4]([OH:5])[CH2:3]1.[C:18](Cl)(=[O:34])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>CN(C)C=O>[C:18]([O:8][CH2:7][C@H:6]1[O:9][C@@H:2]([N:10]2[CH:17]=[CH:16][C:14]([NH2:15])=[N:13][C:11]2=[O:12])[CH2:3][C@@H:4]1[OH:5])(=[O:34])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]

참가 물질

4

반응물 2

HCID 8206Palmitoyl chlorideHCID 107488Deoxycytidine hydrochloride

생성물 1

HCID 154843895'-O-palmitoyldeoxycytidine

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

5′-O-palmitoyldeoxycytidine is synthesized by reacting deoxycytidine hydrochloride with 1.1 equivalents palmitoyl chloride in dry dimethylformamide.

출처 및 근거

ORD 기록
ord-09ab98b34f8845959d78208328b3b25d
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06297222B1

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