참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | 4,6-Dichloropyrimidine | HCID 70943 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-(6-Chloropyrimidin-4-yl)morpholine | HCID 796070 | — |
반응 단계
45.0 g (302.1 mmol) of 4,6-dichloropyrimidine are initially charged in 450 ml of water. 26.3 g (302.1 mmol) of morpholine are added, and the mixture is stirred at 90° C. for 16 h. The mixture is then cooled to 0° C., and the precipitate formed is filtered off. The precipitate is washed once with 50 ml of water and air-dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08524699B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-d1f9ab0e57eb42c6b0e421bc0e8cbff6 |
|---|
| 출처 메모 | uspto-grants-2013_09 |
|---|
