Trimethylsilylacetylene → HCID 68895269, 화합물

HRID 38223노트

반응식

HRID 38223 반응식
I[C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2.[CH3:11][Si:12]([C:15]#[CH:16])([CH3:14])[CH3:13]>>[CH3:11][Si:12]([C:15]#[C:16][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2)([CH3:14])[CH3:13]

참가 물질

3

반응물 2

HCID 66111TrimethylsilylacetyleneHCID 247282194-iodo-1H-indazole

생성물 1

HCID 68895269HCID 68895269, 화합물수율 57%

실험 절차

In an adaption of GP 8a, 4-Iodo-1H-indazole (1.00 g, 4.10 mmol) was reacted with trimethylsilyl acetylene (0.61 mL, 4.30 mmol) at 90° C. for 5 h to give 498 mg (57%) of pure 4-(trimethylsilyl)ethynyl-1H-indazole.

출처 및 근거

ORD 기록
ord-bfc9ed4a932f44f5a935a2500c8cd2e4
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08524724B2

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