Nicotinic Acid → HCID 18360422, 화합물
반응식
[NH2:1][C:2]1[N:3]=[CH:4][N:5]([CH2:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:6]=1[C:7]([NH2:9])=[O:8].[C:19](O)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[N:22][CH:21]=1>>[C:13]1([CH2:12][CH2:11][CH2:10][N:5]2[C:6]([C:7]([NH2:9])=[O:8])=[C:2]([NH:1][C:19]([C:20]3[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=3)=[O:26])[N:3]=[CH:4]2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1참가 물질
3
실험 절차
An amidation reaction and post-treatment were carried out following the conditions of Example 17, using 2.00 g (8.19 mmol) of 4-amino-1-(3-phenylpropyl)-5-imidazolecarboxamide prepared in the same manner as in Example 114 and nicotinic acid instead of 3-pyridylacetic acid hydrochloride to obtain crude 1-(3-phenylpropyl)-4-(3-pyridylcarbonylamino)-5-imidazolecarboxamide.
후처리
- customAn amidation reaction
출처 및 근거
- ORD 기록
- ord-bf23285f48c04790a519db7b5548b355
- 출처 데이터셋
- uspto-grants-2001_10