Benzaldehyde → 2-(2-Phenylethenyl)-8-Quinolinol

HRID 382883

반응식

HRID 382883 반응식
[OH:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([CH3:12])[CH:8]=[CH:7]2.[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[C:14]1([CH:13]=[CH:12][C:9]2[CH:8]=[CH:7][C:6]3[C:11](=[C:2]([OH:1])[CH:3]=[CH:4][CH:5]=3)[N:10]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 240BenzaldehydeHCID 132242-Methyl-8-hydroxyquinoline

생성물 1

HCID 4698252-(2-Phenylethenyl)-8-Quinolinol

실험 절차

A mixture of 8-hydroxyquinaldine (10.02 g) and benzaldehyde (16.8 mL) is heated at reflux overnight. The reaction is cooled to room temperature and vacuum distilled. After the excess benzaldehyde has distilled off, the residue remaining in the flask is dissolved in hot 95% EtOH. Any undissolved material is filtered off. The EtOH filtrate is cooled slowly to give the product as light yellow crystals (5.17 g).

후처리

  1. temperatureis heated
  2. temperatureat reflux overnight
  3. distillationvacuum distilled
  4. distillationAfter the excess benzaldehyde has distilled off
  5. dissolutionis dissolved in hot 95% EtOH
  6. filtrationAny undissolved material is filtered off
  7. temperatureThe EtOH filtrate is cooled slowly

출처 및 근거

ORD 기록
ord-9769d0eac7db4f42a2218a50fc74dd7e
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06310211B1

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