참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | Ethyl 2-chloro-5-phenylthiazole-4-carboxylate | HCID 59291332 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Chloro-5-phenylthiazole-4-carboxylic acid | HCID 21651637 | — |
반응 단계
To a solution of ethyl 2-chloro-5-phenylthiazole-4-carboxylate in THF was added a 1 M aqueous KOH solution, followed by stirring at 60° C. for 30 minutes. To the reaction mixture was added 1 M hydrochloric acid, and the solid precipitated was collected by filtration to obtain 2-chloro-5-phenylthiazole-4-carboxylic acid as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08367696B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_02 |
|---|
| ORD ID | ord-04fa5b16812c41a681063f426068f445 |
|---|
| 출처 메모 | uspto-grants-2013_02 |
|---|
