Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide → N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide | HCID 58098809 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide | HCID 58098633 | 98.4% |
반응 단계
To a solution of N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide (430 mg) in EtOH (10 mL) was added Pd/C (200 mg) and was charged with H2 (1 atm). After stirring for 3 h, Pd/C was removed by filtration and the filtrate was concentrated to give N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide (380 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08367689B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-d1633ed141fa4999a8ebff19c862db2f |
| 출처 메모 | uspto-grants-2013_02 |