Rac-[1-(3,4-dichloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester → Rac-[2-(4-sec-butoxy-phenyl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
반응식
[C:1]([O:5][C:6](=[O:26])[NH:7][CH:8]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[C:20]([Cl:25])[CH:19]=1)[C:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=[O:10])([CH3:4])([CH3:3])[CH3:2]>CC(O)CC>[C:1]([O:5][C:6](=[O:26])[NH:7][CH:8]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[C:20]([Cl:25])[CH:19]=1)[C:9]([C:11]1[CH:12]=[CH:13][C:14]([O:17][CH:8]([CH2:9][CH3:11])[CH3:18])=[CH:15][CH:16]=1)=[O:10])([CH3:4])([CH3:2])[CH3:3]참가 물질
3
실험 절차
The title compound was prepared from rac-[1-(3,4-dichloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and 2-butanol in analogy to Example 9c): MS (ISP): 452.1 and 454.0 (M+H)+, 352.1 and 354.1 ((M-Boc)+H)+ (100%).
출처 및 근거
- ORD 기록
- ord-1f732e2fb3aa4ff0b0e5cf0122dc8180