Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate → Trimethyl 1,2,4-benzenetricarboxylate

HRID 385203노트

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HRID 385203 반응식
[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH:6]=[CH:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12]>C1(C)C=CC=C(C)C=1.[Pt]>[C:15]([O:17][CH3:18])(=[O:16])[C:1]1[C:2](=[CH:3][C:4](=[CH:5][CH:6]=1)[C:7]([O:9][CH3:10])=[O:8])[C:11]([O:13][CH3:14])=[O:12]

참가 물질

4

반응물 1

HCID 60136166Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate

생성물 1

HCID 17159Trimethyl 1,2,4-benzenetricarboxylate수율 65%

시약·촉매·용매 2

HCID 23939Platinum촉매HCID 7929M-Xylene용매

실험 절차

Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (200 mg, 0.78 mmol) is mixed with 305 mg of 5 percent by weight platinum on a carbon support in m-xylene (30 ml). The reaction mixture is refluxed with the reflux apparatus being open to air for 4 days. The residual platinum on carbon is then filtered off and the filtrate is concentrated down to a clear colorless gel. The desired product is obtained with a 65 percent yield. The yield is determined by GC/MS using a dodecane as an internal standard.

후처리

  1. temperatureThe reaction mixture is refluxed with the reflux apparatus
  2. filtrationThe residual platinum on carbon is then filtered off
  3. concentrationthe filtrate is concentrated down to a clear colorless gel

출처 및 근거

ORD 기록
ord-6bbaf649e24e495d812865463725d1a4
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367858B2

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