Iodine → Muconic Acid

HRID 385208

반응식

HRID 385208 반응식
[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]\[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].II>C(O)CC>[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[C:6]([OH:8])=[O:7]

참가 물질

4

반응물 2

HCID 807IodineHCID 5280614(2E,4Z)-2,4-Hexadienedioic acid

생성물 1

HCID 5356793Muconic Acid수율 73%

시약·촉매·용매 1

HCID 10311-Propanol용매

실험 절차

cis,trans-Muconic acid (103 mg, 0.725 mmol) is dissolved in n-propanol (10 mL) at room temperature and a crystal of iodine (10 mg, 0.04 mmol) is added. The reaction mixture is allowed to stir at room temperature for 24 hours. The precipitate is filtered, washed with acetonitrile and dried under reduced pressure to yield 75 mg of trans,trans-muconic acid, a 73 percent yield.

후처리

  1. filtrationThe precipitate is filtered
  2. washwashed with acetonitrile
  3. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-43b6087262e946d986e929fdc93548e2
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367858B2

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