Dimethylformamide dimethyl acetal → HCID 178484334, 화합물

HRID 385741노트

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HRID 385741 반응식
[N+:1]([C:4]1[S:8][C:7]([C:9]([NH2:11])=[O:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].CO[CH:14](OC)[N:15]([CH3:17])[CH3:16]>CN(C=O)C>[CH3:14][N:15](/[CH:17]=[N:11]/[C:9]([C:7]1[S:8][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=1)=[O:10])[CH3:16]

참가 물질

4

반응물 2

HCID 78373Dimethylformamide dimethyl acetalHCID 3147105-Nitrothiophene-2-carboxamide

생성물 1

HCID 178484334HCID 178484334, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

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온도
120 °C

실험 절차

5-Nitrothiophene-2-carboxamide (5.80 g, 33.7 mmol) was combined with N,N-dimethylformamide dimethyl acetal (75 mL, 560 mmol) and stirred at 120° C. overnight (added 10 mL DMF to help dissolve the starting material). The red-brown solution was cooled to room temperature, at which point a solid precipitated from solution. The solid was isolated by filtration, washed with Et2O, and dried to provide the title compound as tan crystals.

후처리

  1. dissolutionto help dissolve the starting material)
  2. temperatureThe red-brown solution was cooled to room temperature, at which point a solid
  3. customprecipitated from solution
  4. customThe solid was isolated by filtration
  5. washwashed with Et2O
  6. customdried

출처 및 근거

ORD 기록
ord-78ab10ec18db451f96a7d192dfc996a2
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367706B2

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