Hydrochloric Acid → HCID 178516515, 화합물

반응식

C([O:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([N:10]2[CH2:14][CH2:13][CH:12]([OH:15])[CH2:11]2)[N:5]=1)C.Cl>>[OH:15][CH:12]1[CH2:13][CH2:14][N:10]([C:6]2[N:5]=[C:4]([OH:3])[CH:9]=[CH:8][N:7]=2)[CH2:11]1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 595262421-(4-Ethoxypyrimidin-2-yl)pyrrolidin-3-ol

생성물 1

HCID 178516515HCID 178516515, 화합물

실험 절차

1-(4-Ethoxypyrimidin-2-yl)pyrrolidin-3-ol (1.0 g, 4.8 mol) was combined with 6M HCl (24 mL, 144 mmol) and heated to reflux overnight. The mixture was concentrated in vacuo to give the title compound.

후처리

temperatureheated
temperatureto reflux overnight
concentrationThe mixture was concentrated in vacuo

출처 및 근거

ORD 기록: ord-6c4aae4efd6141c3b501918b973eafbe
출처 데이터셋: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08367706B2

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