8-(2-Dimethylamino-4-nitro-phenyl)purin-6-one → 8-(4-Amino-2-dimethylamino-phenyl)purin-6-one

HRID 3864노트

반응식

HRID 3864 반응식
[CH3:1][N:2]([CH3:22])[C:3]1[CH:8]=[C:7]([N+:9]([O-])=O)[CH:6]=[CH:5][C:4]=1[C:12]1[N:20]=[C:19]2[C:14](=[N:15][CH:16]=[N:17][C:18]2=[O:21])[N:13]=1.[H][H]>CO.[Ni]>[NH2:9][C:7]1[CH:6]=[CH:5][C:4]([C:12]2[N:20]=[C:19]3[C:14](=[N:15][CH:16]=[N:17][C:18]3=[O:21])[N:13]=2)=[C:3]([N:2]([CH3:22])[CH3:1])[CH:8]=1

참가 물질

5

반응물 2

HCID 201532228-(2-Dimethylamino-4-nitro-phenyl)purin-6-oneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 201532408-(4-Amino-2-dimethylamino-phenyl)purin-6-one

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

An amount of 0.9 gm of 8-(2-dimethylamino-4-nitro-phenyl)purin-6-one is hydrogenated in 50 ml of methanol in the presence of 0.5 gm of Raney nickel at ambient temperature and under 5 bars of pressure with hydrogen for three hours until the calculated quantity has been taken up. After the catalyst has been subjected to suction filtration, the filtrate is evaporated to dryness in vacuo.

후처리

  1. filtrationAfter the catalyst has been subjected to suction filtration
  2. customthe filtrate is evaporated to dryness in vacuo

출처 및 근거

ORD 기록
ord-7272044c980b48afb3322c501ec35ccc
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04722929

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