Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, 화합물

HRID 389051노트

반응식

HRID 389051 반응식
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

참가 물질

3

반응물 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

생성물 1

HCID 21925070HCID 21925070, 화합물

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

후처리

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

출처 및 근거

ORD 기록
ord-2775abbed9244b129ae3cb81da301a7e
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08378099B2

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