Benzyl mercaptan → 1-Benzylsulfanyl-3-bromo-2-trifluoromethyl-benzene

HRID 389654

반응식

HRID 389654 반응식
[C:1]1([CH2:7][SH:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12](F)[C:11]=1[C:17]([F:20])([F:19])[F:18]>>[CH2:7]([S:8][C:12]1[CH:13]=[CH:14][CH:15]=[C:10]([Br:9])[C:11]=1[C:17]([F:18])([F:20])[F:19])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 7509Benzyl mercaptanHCID 27733452-Bromo-6-fluorobenzotrifluoride

생성물 1

HCID 671552591-Benzylsulfanyl-3-bromo-2-trifluoromethyl-benzene

실험 절차

Phenyl-methanethiol (4.g g, 37.0 mmol) was treated with commercially available 1-bromo-3-fluoro-2-trifluoromethyl-benzene (10.0 g, 41.1 mmol) in close analogy to the procedure described in step 5.3). The crude product (10.5 g) after workup was used as such in the next reaction step without purification by chromatography.

후처리

  1. customsuch in the next reaction step
  2. customwithout purification by chromatography

출처 및 근거

ORD 기록
ord-e82cb9c16d524ad382d59b2d011bdb18
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08378092B2

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