Water → 2-Hydroxy-1-(3-methylphenyl)ethan-1-one

HRID 389896

반응식

HRID 389896 반응식
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[CH:6]=1)=[O:4].[OH2:12]>C(#N)C>[OH:12][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[CH:6]=1)=[O:4]

참가 물질

4

반응물 2

HCID 962WaterHCID 100361292-Bromo-1-(3-methylphenyl)ethan-1-one

생성물 1

HCID 183729052-Hydroxy-1-(3-methylphenyl)ethan-1-one

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A solution of 2-bromo-1-(3-methylphenyl)ethanone (1 g) in acetonitrile (2.5 mL) and water (13 mL) is treated under microwave irradiation (125° C., 50 min). The same experiment is repeated three times. All the vials are collected, extracted with DCM, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.

후처리

  1. customAll the vials are collected
  2. extractionextracted with DCM
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under vacuum

출처 및 근거

ORD 기록
ord-53b1fb3a11334045a8e1fdc82626b016
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383608B2

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