Pyridine → (4-Bromo-2-chlorophenyl) acetate

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([Cl:9])[CH:3]=1.[C:10](OC(=O)C)(=[O:12])[CH3:11].N1C=CC=CC=1>>[C:10]([O:8][C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=1[Cl:9])(=[O:12])[CH3:11]

참가 물질

반응물 3

HCID 1049Pyridine

HCID 7918Acetic Anhydride

HCID 198594-Bromo-2-chlorophenol

생성물 1

HCID 190463(4-Bromo-2-chlorophenyl) acetate

실험 절차

Preparation according to Preparation 16 using 4-bromo-2-chlorophenol (6 g, 29 mmol) and acetic anhydride (13.4 g, 130 mmol) in pyridine (10.5 ml, 130 mmol). Yield 7.4 g. MS m/z (rel. intensity, 70 eV) 210 (25), 208 (bp), 206 (79), 63 (21), 62 (9), 250 (M+, 8).

후처리

customPreparation

출처 및 근거

ORD 기록: ord-a4f9b6d3118c4131ab6577fa07187996
출처 데이터셋: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08524766B2

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