Hydrochloric Acid → Ethyl 7-mercaptochromane-2-carboxylate

HRID 39038노트

반응식

HRID 39038 반응식
C([Si](C(C)C)(C(C)C)[S:5][C:6]1[CH:15]=[C:14]2[C:9]([CH2:10][CH2:11][CH:12]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[O:13]2)=[CH:8][CH:7]=1)(C)C.Cl>CCO>[SH:5][C:6]1[CH:15]=[C:14]2[C:9]([CH2:10][CH2:11][CH:12]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[O:13]2)=[CH:8][CH:7]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 66878159Ethyl 7-[(triisopropylsilyl)thio]chromane-2-carboxylate

생성물 1

HCID 66878558Ethyl 7-mercaptochromane-2-carboxylate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

To a mixture of ethyl 7-[(triisopropylsilyl)thio]chromane-2-carboxylate (5.6 g, 14.2 mmol) in EtOH (100 ml) was added concentrated HCl (4 ml) and the mixture was stirred at room temperature for 3 h. Evaporation to dryness gave the title compound. Yield: 3.4 g. MS m/z (rel. intensity, 70 eV) 238 (M+, 75), 165 (bp), 163 (56), 132 (50), 131 (43).

후처리

  1. customEvaporation to dryness

출처 및 근거

ORD 기록
ord-835eeba1804541ff8e9865b126b437b6
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08524766B2

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