3-Cyanopyridine → 5-(3-Pyridyl)tetrazole
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]#[N:8])[CH:2]=1.[N-:9]=[N+:10]=[N-:11].[Na+].[Cl-].[NH4+].Cl>CN(C=O)C.O>[N:8]1[NH:9][N:10]=[N:11][C:7]=1[C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1참가 물질
7
실험 절차
30 g (288 mmol) of 3-pyridinecarbonitrile, 28.1 g (432 mmol) of sodium azide (NaN3), and 23.1 g (432 mmol) of ammonium chloride were dissolved in 200 mL of DMF. The solution was reacted at 100° C. for 24 hours. Then, water was added to the acquired reactant. The resulting product was neutralized with hydrochloric acid and then filtered, obtaining 19.6 g (Y=46%) of a white solid.
후처리
- customThe solution was reacted at 100° C. for 24 hours
- filtrationfiltered
- customobtaining 19.6 g (Y=46%) of a white solid
출처 및 근거
- ORD 기록
- ord-41afb95e81ff48db9c82f539d8673436
- 출처 데이터셋
- uspto-grants-2013_02
- 특허 번호
- US08383932B2
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