Dicyclopentadiene → 8-(2,2,2-Trifluoro-1-trifluoromethyl-1-hydroxyethyl)tetracyclo[4.4.0.12,5.17,10]dodec-3-ene

HRID 392011

반응식

HRID 392011 반응식
[F:1][C:2]([F:13])([F:12])[C:3]([C:8]([F:11])([F:10])[F:9])([OH:7])[CH2:4][CH:5]=C.[CH2:14]1[CH:18]2[CH:19]3[CH:23]=[CH:22][CH:21]([CH:17]2[CH:16]=[CH:15]1)[CH2:20]3>>[F:1][C:2]([F:12])([F:13])[C:3]([CH:4]1[CH2:5][CH:14]2[CH2:15][CH:16]1[CH:17]1[CH:18]2[CH:19]2[CH2:20][CH:21]1[CH:22]=[CH:23]2)([C:8]([F:10])([F:9])[F:11])[OH:7]

참가 물질

3

반응물 2

HCID 6492DicyclopentadieneHCID 3288704-Penten-2-ol, 1,1,1-trifluoro-2-(trifluoromethyl)-

생성물 1

HCID 206170878-(2,2,2-Trifluoro-1-trifluoromethyl-1-hydroxyethyl)tetracyclo[4.4.0.12,5.17,10]dodec-3-ene수율 22.2%

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온도
190 °C

실험 절차

A 500 ml autoclave was charged with 230 g of 1,1-bis(trifluoromethyl)-3-butenol, 73 g of dicyclopentadiene, and 0.15 g of 2,6-di-t-butylparacresol, and the mixture was heated at 190° C. for 12 hours. The reaction solution was cooled to room temperature and purified by distillation to obtain 40 g of 8-(2,2,2-trifluoro-1-trifluoromethyl-1-hydroxyethyl)tetracyclo[4.4.0.12,5.17,10]dodec-3-ene of the following formula (13).

후처리

  1. temperatureThe reaction solution was cooled to room temperature
  2. distillationpurified by distillation

출처 및 근거

ORD 기록
ord-c5a8c281d9034da7adddb676a06667da
출처 데이터셋
uspto-grants-2004_10
특허 번호
US06800414B2

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