Triethoxychlorosilane → Chlorodifluoroacetic acid, triethoxysilyl ester

HRID 392948

반응식

HRID 392948 반응식
[Cl:1][C:2]([F:7])([F:6])[C:3]([O-:5])=[O:4].[Na+].Cl[Si:10]([O:17][CH2:18][CH3:19])([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13]>CCOCC>[Cl:1][C:2]([F:7])([F:6])[C:3]([O:5][Si:10]([O:17][CH2:18][CH3:19])([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13])=[O:4]

참가 물질

4

반응물 2

HCID 78398TriethoxychlorosilaneHCID 2734985Sodium chlorodifluoroacetate

생성물 1

HCID 23523584Chlorodifluoroacetic acid, triethoxysilyl ester

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

반응 조건

온도
-70 °C

실험 절차

15.246 g (0.10 mol) sodium chlorodifluoroacetate, is dissolved to 100 mL Et2O and cooled to −70° C. 19.7 mL (0.10 mol, 19.872 g) chlorotriethoxysilane in Et2O (50 mL) was added dropwise to reaction solution. The solution was stirred for over night allowing it to warm up to room temperature. NaCl is removed by filtration and solution evaporated to dryness to result clear colourless liquid, chlorodifluoroacetic acid, triethoxysilyl ester.

후처리

  1. temperatureto warm up to room temperature
  2. customNaCl is removed by filtration and solution
  3. customevaporated to dryness

출처 및 근거

ORD 기록
ord-952c4637cec247c382f31cb28c094e32
출처 데이터셋
uspto-grants-2004_10
특허 번호
US06803476B2

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