Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → Ethyl (3S)-piperidine-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Ethyl (S)-3-Piperidinecarboxylate D-Tartrate | HCID 14183617 | — |
| 생성물 | Ethyl (3S)-piperidine-3-carboxylate | HCID 187784 | 112.8% |
반응 단계
To 13.0 g of ethyl (3S)-3-piperidinecarboxylate D(−)-tartarate which was synthesized following the method of P. Magnus, et al. [J. Org. Chem. Vol. 56, 1166-1170 (1991)], 3N aqueous sodium hydroxide solution was added to render the former basic, followed by extraction with chloroform and drying over anhydrous magnesium sulfate. Distilling the solvent off under reduced pressure, 7.50 g of the title compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06809108B1 |
| 출처 데이터셋 | uspto-grants-2004_10 |
| ORD ID | ord-2634489c1dd6442fbb237c8936f4cd17 |
| 출처 메모 | uspto-grants-2004_10 |