Lithium Hydroxide → HCID 22647452, 화합물
반응식
C([O:3][C:4](=[O:32])[CH:5]([O:29][CH2:30][CH3:31])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]2[N:16]=[C:17]([C:21]3[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=3)[S:18][C:19]=2[CH3:20])=[CH:9][C:8]=1[CH3:28])C.[Li+].[OH-]>>[Cl:27][C:24]1[CH:25]=[CH:26][C:21]([C:17]2[S:18][C:19]([CH3:20])=[C:15]([CH2:14][O:13][C:10]3[CH:11]=[CH:12][C:7]([CH2:6][CH:5]([O:29][CH2:30][CH3:31])[C:4]([OH:32])=[O:3])=[C:8]([CH3:28])[CH:9]=3)[N:16]=2)=[CH:22][CH:23]=1참가 물질
3
실험 절차
In analogy to the procedure described in example 10 d], [rac]-3-{4-[2-(4-chloro-phenyl)-5-methyl-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid ethyl ester was treated with LiOH to obtain [rac]-3-{4-[2-(4-chloro-phenyl)-5-methyl-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid as colorless solid.
후처리
- customdescribed in example 10 d
출처 및 근거
- ORD 기록
- ord-68ca0d5a4b6c4a708b2ba51f322862db
- 출처 데이터셋
- uspto-grants-2004_10