Hydrochloric Acid → HCID 18173116, 화합물

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[O:1]=[C:2]1[CH2:7][CH:6]2[CH:8]([C:9](O)=O)[CH:3]1[CH2:4][CH2:5]2.[CH2:12]([N:15]1[C:22]([NH2:23])=[C:21]([NH2:24])[C:19](=[O:20])[N:18]([CH2:25][CH2:26][CH3:27])[C:16]1=[O:17])[CH2:13][CH3:14].Cl>>[O:1]=[C:2]1[CH2:7][CH:6]2[CH:8]([C:9]3[NH:24][C:21]4[C:19](=[O:20])[N:18]([CH2:25][CH2:26][CH3:27])[C:16](=[O:17])[N:15]([CH2:12][CH2:13][CH3:14])[C:22]=4[N:23]=3)[CH:3]1[CH2:4][CH2:5]2

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 50986055,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione

HCID 12301617101915-50-8

생성물 1

HCID 18173116HCID 18173116, 화합물

실험 절차

2-Oxo-bicyclo[2.2.1]heptane-7-carboxylic acid (308 mg) was couple to 1,3-Dipropyl-5,6-diaminouracil.HCl (576 mg) and cyclized using the procedures from Example 1. Yield: 320 mg. Mass (ES+ 345).

출처 및 근거

ORD 기록: ord-90b96fc01ddc464ebd17552d276968c7
출처 데이터셋: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06605600B1

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