2-Methylimidazole → HCID 9815053, 화합물

반응식

[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.[H-].[Na+].Cl[CH2:10][C:11]1[CH:12]=[N:13][N:14]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[C:18]([Cl:23])[CH:17]=2)[CH:15]=1>>[Cl:23][C:18]1[CH:17]=[C:16]([N:14]2[CH:15]=[C:11]([CH2:10][N:3]3[CH:4]=[CH:5][N:6]=[C:2]3[CH3:1])[CH:12]=[N:13]2)[CH:21]=[CH:20][C:19]=1[Cl:22]

참가 물질

반응물 3

HCID 127492-Methylimidazole

HCID 24758Sodium hydride

HCID 234450154-chloromethyl-1-(3,4-dichloro-phenyl)-1H-pyrazole

생성물 1

HCID 9815053HCID 9815053, 화합물

실험 절차

2-Methylimidazole was deprotonated with sodium hydride and then treated with 4-chloromethyl-1-(3,4-dichloro-phenyl)-1H-pyrazole. Extractive and chromatographic workup gave the title compound as a white crystalline solid. Mp. 176-177° C. (AcOEt), MS: m/e=307(M+H+).

출처 및 근거

ORD 기록: ord-6ea2d1d0ca424cdd9a68ce736e0eb576
출처 데이터셋: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06610723B2

반응 노트

불러오는 중…