Hydrochloric Acid → Ethyl cyclopropanecarboximidate hydrochloride

HRID 397948노트

반응식

HRID 397948 반응식
[ClH:1].[CH:2]1([C:5]#[N:6])[CH2:4][CH2:3]1.[CH2:7]([O:9]CC)[CH3:8]>CCO>[ClH:1].[CH2:7]([O:9][C:5]([CH:2]1[CH2:4][CH2:3]1)=[NH:6])[CH3:8]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 79637Cyclopropanecarbonitrile

생성물 1

HCID 20026660Ethyl cyclopropanecarboximidate hydrochloride수율 59%

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
0 °C

실험 절차

A steady stream of HCl gas was slowly passed through a solution of cyclopropancarbonitril (25 g, 373 mmol) in EtOH (17.2 ml). After 15 h the reaction mixture was cooled to 0° C. and diethylether was added dropwise. The precipitated title compound was filtered and obtained as a colourless crystalline material (32.9 g, 220 mmol, 59%). MS: m/e=112.2 (M−H).

후처리

  1. customThe precipitated title compound
  2. filtrationwas filtered

출처 및 근거

ORD 기록
ord-82b83684b24e4704b279c0b7d2caca4b
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06610723B2

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