Potassium Hydroxide → (1, 1-dimethyl-2-(4-oxo-5-(2'-(N-triphenylmethyltetrazol-5-yl)biphenyl-4-ylmethyl)-2,3,4,5-tetrahydro-1H-naphtho[2,1-b]azepin-3-ylcarbamoyl)ethyl)-carbamic acid tert-butyl ester

반응식

[OH-].[K+].[C:3]([O:7][C:8](=[O:33])[NH:9][C:10]([CH3:32])([CH3:31])[CH2:11][C:12](=[O:30])[NH:13][CH:14]1[C:20](=[O:21])[NH:19][C:18]2[CH:22]=[CH:23][C:24]3[C:29]([C:17]=2[CH2:16][CH2:15]1)=[CH:28][CH:27]=[CH:26][CH:25]=3)([CH3:6])([CH3:5])[CH3:4].Br[CH2:35][C:36]1[CH:41]=[CH:40][C:39]([C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][C:43]=2[C:48]2[N:52]([C:53]([C:66]3[CH:71]=[CH:70][CH:69]=[CH:68][CH:67]=3)([C:60]3[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=3)[C:54]3[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=3)[N:51]=[N:50][N:49]=2)=[CH:38][CH:37]=1.[Cl-].[NH4+]>CS(C)=O.C(OCC)(=O)C.O>[C:3]([O:7][C:8](=[O:33])[NH:9][C:10]([CH3:32])([CH3:31])[CH2:11][C:12](=[O:30])[NH:13][CH:14]1[C:20](=[O:21])[N:19]([CH2:35][C:36]2[CH:37]=[CH:38][C:39]([C:42]3[CH:47]=[CH:46][CH:45]=[CH:44][C:43]=3[C:48]3[N:52]([C:53]([C:66]4[CH:71]=[CH:70][CH:69]=[CH:68][CH:67]=4)([C:60]4[CH:61]=[CH:62][CH:63]=[CH:64][CH:65]=4)[C:54]4[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=4)[N:51]=[N:50][N:49]=3)=[CH:40][CH:41]=2)[C:18]2[CH:22]=[CH:23][C:24]3[C:29]([C:17]=2[CH2:16][CH2:15]1)=[CH:28][CH:27]=[CH:26][CH:25]=3)([CH3:6])([CH3:4])[CH3:5]