N,N-diethylpiperidin-4-amine dihydrochloride → N,N-diethylpiperidin-4-amine
반응식
Cl.Cl.[CH2:3]([N:5]([CH2:12][CH3:13])[CH:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)[CH3:4]>O.[OH-].[Na+]>[CH2:12]([N:5]([CH2:3][CH3:4])[CH:6]1[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]1)[CH3:13]참가 물질
4
실험 절차
To a solution of 4-(diethylamino)piperidine dihydrochloride (3.0 g, 0.019 mmol) in water (20 mL), 2M sodium hydroxide solution (5.0 mL) was added at ambient temperature. The mixture was stirred for 30 min. The solvent was removed under reduced pressure, and methanol (10 mL) was added to the crude material, then the residue was removed by filtration. The filtrate was concentrated and dried to afford 4-(diethylamino)piperidine (1.7 g, y. 77%) as solid.
후처리
- customThe solvent was removed under reduced pressure, and methanol (10 mL)
- additionwas added to the crude material
- customthe residue was removed by filtration
- concentrationThe filtrate was concentrated
- customdried
출처 및 근거
- ORD 기록
- ord-e3c7ab6f7b484b4da9c0182a6621a93e
- 출처 데이터셋
- uspto-grants-2014_06
- 특허 번호
- US08742113B2
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