Dimethyl Sulfoxide → L-Methionine

HRID 402970

반응식

HRID 402970 반응식
Br.Br[CH2:3][CH2:4][CH:5]([NH2:9])[C:6]([OH:8])=[O:7].[CH3:10][S:11](C)=[O:12]>>[NH2:9][C@H:5]([C:6]([OH:8])=[O:7])[CH2:4][CH2:3][S:11][CH3:10].[NH2:9][C@H:5]([C:6]([OH:8])=[O:7])[CH2:4][CH2:3][OH:12]

참가 물질

4

반응물 2

HCID 679Dimethyl SulfoxideHCID 138779922-Amino-4-bromobutanoic acid hydrobromide

생성물 2

HCID 6137L-Methionine수율 82%HCID 12647L-Homoserine수율 2.6%

실험 절차

4-Bromo-2-aminobutanoic acid hydrobromide (1 eq.) was treated with sodium methane thiolate (3.2 eq.) in DMSO (25 eq.) at 80° C. for 1 hour. Methionine (82% yield) and homoserine (2.6% yield) were obtained.

출처 및 근거

ORD 기록
ord-a4ac0a7adf914a1885be15bf342be42a
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08742170B2

연결된 노트

불러오는 중…