Propanal → Tert-butyl 4-(propylamino)piperidine-1-carboxylate

반응식

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][CH2:15][CH3:16])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH:17](=O)CC>>[C:1]([O:5][C:6]([N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][CH2:16][CH3:17])[CH2:12][CH2:13]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 527Propanal

HCID 18374730tert-Butyl 4-(ethylamino)piperidine-1-carboxylate

생성물 1

HCID 22458258Tert-butyl 4-(propylamino)piperidine-1-carboxylate

실험 절차

The title compound was synthesized by the method, described for 4-Ethylamino-piperidine-1-carboxylic acid tert-butyl ester (16), using propionaldehyde instead of acetaldehyde. Rt=1.43 min (Method B). Detected mass: 243.2 (M+H+).

출처 및 근거

ORD 기록: ord-92a62a9809114e3395f56ec899aca41c
출처 데이터셋: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08748614B2

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