Hydrochloric Acid → HCID 68593090, 화합물

반응식

BrC1C=C2C(C=CN=C2)=CC=1[Cl:12].[Br:13][C:14]1[CH:23]=[C:22]2[C:17]([CH:18]=[CH:19][N:20]=[CH:21]2)=[CH:16][C:15]=1[S:24][CH2:25][CH:26]1[CH2:30][CH2:29][NH:28][CH2:27]1.C(OC(N1CCC(CBr)C1)=O)(C)(C)C.Cl>>[ClH:12].[Br:13][C:14]1[CH:23]=[C:22]2[C:17]([CH:18]=[CH:19][N:20]=[CH:21]2)=[CH:16][C:15]=1[S:24][CH2:25][CH:26]1[CH2:30][CH2:29][NH:28][CH2:27]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 68591666HCID 68591666, 화합물

HCID 685930337-Bromo-6-chloroisoquinoline

생성물 1

HCID 68593090HCID 68593090, 화합물

실험 절차

Starting from 7-Bromo-6-chloroisoquinoline (265) and 3-Bromomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 7-Bromo-6-(pyrrolidin-3-ylmethylsulfanyl)-isoquinoline could be obtained according to the procedures described for 272, 267, 268 as the hydrochloride. Rt=0.72 min (Method B). Detected mass: 323.1/325.2 (M+H+).