Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Oxoglutaric Acid → HCID 131728122, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Oxoglutaric Acid | HCID 51 | — |
| 반응물 | (2R,4aR,10bR)-6-(2-Dimethylamino-4-methoxy-pyrimidin-5-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydro-phenanthridin-2-ol | HCID 11853488 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | HCID 131728122 | HCID 131728122 | 71% |
반응 단계
(2R,4aR,10bR)-6-(2-Dimethylamino-4-methoxy-pyrimidin-5-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydro-phenanthridin-2-ol ((42.7 mg, 0.1 mmol) are dissolved in 0.5 ml of acetone. 16.1 mg (0.11 mmol) of 2-oxo-pentanedioic acid (dissolved in 0.5 ml of acetone) are added. The crystals are filtered off and dried to obtain 40.6 mg (71%) of the title compound (m.p.: 124° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08754218B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-5a7d3c0d8c7d4cc283866888daa63ff7 |
| 출처 메모 | uspto-grants-2014_06 |