Methylamine → Methyl 4-(methylamino)-3-nitrobenzoate

HRID 410719

반응식

HRID 410719 반응식
Cl[C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][NH2:16]>CN(C=O)C>[CH3:9][O:8][C:6](=[O:7])[C:5]1[CH:10]=[CH:11][C:2]([NH:16][CH3:15])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 735797Methyl 4-chloro-3-nitrobenzoate

생성물 1

HCID 7650848Methyl 4-(methylamino)-3-nitrobenzoate

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

4-Methylamino-3-nitro-benzoic acid methyl ester (822 mg) was prepared by following General Procedure A starting from methyl 4-chloro-3-nitrobenzoate (1.0 g) and methylamine (2 M in THF, 6.95 mL) in DMF. The crude product was used in the next step without further purification.

후처리

  1. customThe crude product was used in the next step without further purification

출처 및 근거

ORD 기록
ord-7f3c860dc8984f65a22b71e866d028cd
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759535B2

연결된 노트

불러오는 중…