Methylamine → (4-Methanesulfonyl-2-nitro-phenyl)methyl-amine

HRID 410955

반응식

HRID 410955 반응식
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][NH2:16]>CN(C=O)C>[CH3:11][S:8]([C:5]1[CH:6]=[CH:7][C:2]([CH2:15][NH2:16])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1)(=[O:10])=[O:9]

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 3131371-Fluoro-4-methanesulfonyl-2-nitrobenzene

생성물 1

HCID 44518858(4-Methanesulfonyl-2-nitro-phenyl)methyl-amine

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

(4-Methanesulfonyl-2-nitro-phenyl)methyl-amine (182 mg) was prepared by following General Procedure A starting from 1-fluoro-4-methanesulfonyl-2-nitro-benzene (219 mg) and methylamine (2 M in THF, 1.0 ml) in DMF (5 mL). The crude product was used in the next step without further purification.

후처리

  1. customThe crude product was used in the next step without further purification

출처 및 근거

ORD 기록
ord-a2c85c829b5f41c3b433ff9774433725
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759535B2

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