N-Dimethylcarbamoylmethyl-4-methylamino-3-nitro-benzamide → 3-Amino-N-dimethylcarbamoylmethyl-4-methylamino-benzamide

HRID 411053

반응식

HRID 411053 반응식
[CH3:1][N:2]([CH3:20])[C:3]([CH2:5][NH:6][C:7](=[O:19])[C:8]1[CH:13]=[CH:12][C:11]([NH:14][CH3:15])=[C:10]([N+:16]([O-])=O)[CH:9]=1)=[O:4]>CO.[Pd]>[NH2:16][C:10]1[CH:9]=[C:8]([CH:13]=[CH:12][C:11]=1[NH:14][CH3:15])[C:7]([NH:6][CH2:5][C:3](=[O:4])[N:2]([CH3:20])[CH3:1])=[O:19]

참가 물질

4

반응물 1

HCID 9303598N-Dimethylcarbamoylmethyl-4-methylamino-3-nitro-benzamide

생성물 1

HCID 673334993-Amino-N-dimethylcarbamoylmethyl-4-methylamino-benzamide수율 98%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

3-Amino-N-dimethylcarbamoylmethyl-4-methylamino-benzamide (700 mg) was prepared by following General Procedure B starting from N-dimethylcarbamoylmethyl-4-methylamino-3-nitro-benzamide (800 mg) and Pd—C (160 mg) in methanol (10 mL).

출처 및 근거

ORD 기록
ord-d890142553bc4e598c7639be7b6c4c30
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759535B2

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