Hydrochloric Acid → (1H-indene-3-yl)methylamine hydrochloride
반응식
O[C:2]1([CH2:11][NH2:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[ClH:13]>C(O)C>[ClH:13].[CH2:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:2]([CH2:11][NH2:12])=[CH:3]1참가 물질
4
실험 절차
Two and three-tenth g of 1-hydroxyindanylmethylamine is dissolved in 100 ml of ethanol saturated with HCl . Reaction mixture is refluxed overnight. It is cooled to room temperature and volatiles are evaporated under reduced pressure. The residue is stirred with 300 ml anhydrous ether. Precipitated solid is filtered and dried affording 2.2 g (85%) of the (1H-indene-3-yl)methylamine hydrochloride having a melting point of 245° C. decomp.
후처리
- customReaction mixture
- temperatureis refluxed overnight
- customvolatiles are evaporated under reduced pressure
- customPrecipitated solid
- filtrationis filtered
- customdried
출처 및 근거
- ORD 기록
- ord-d92c469402694c57b0e870cd7160263c
- 출처 데이터셋
- uspto-grants-1988_12
- 특허 번호
- US04791103
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