3-(2-Nitrophenyl)acrylic acid → Hydrocarbostyril

HRID 414551

반응식

HRID 414551 반응식
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[CH:6]=[CH:7][C:8](O)=[O:9])([O-])=O>C(O)C.[Pd]>[NH:1]1[C:4]2[C:5](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:6][CH2:7][C:8]1=[O:9]

참가 물질

4

반응물 1

HCID 928203-(2-Nitrophenyl)acrylic acid

생성물 1

HCID 64796Hydrocarbostyril

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 25 g of o-nitrocinnamic acid in 250 ml of ethanol was shaken with 2.5 g of 10% palladium on carbon under hydrogen at a pressure of 3 atmospheres. When the theoretical amount of hydrogen had been absorbed the catalyst was filtered off, washed with hot ethanol and the filtrate evaporated under reduced pressure to give 3,4-dihydrocarbosytril, m.p. 168°-169° C.

후처리

  1. customWhen the theoretical amount of hydrogen had been absorbed the catalyst
  2. filtrationwas filtered off
  3. washwashed with hot ethanol
  4. customthe filtrate evaporated under reduced pressure
  5. customto give 3,4-dihydrocarbosytril

출처 및 근거

ORD 기록
ord-5ddb15b8e8ef4e80b242fcfb9689bd83
출처 데이터셋
uspto-grants-1988_12
특허 번호
US04792561

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