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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 416061생성일: 2026년 10월 26일

Sodium hydride → Tert-butyl 2-(4-(3-(4-iodobenzyloxy)-3-(5-(4-(trifluoromethyl) phenyl)thien-2-yl)propyl)-2,3-dichlorophenoxy)-2-methylpropanoate

https://huagongshe.com/reaction/416061

반응식

참여 물질

역할이름HCID투입량
반응물Sodium hydrideHCID 24758—
반응물4-Iodobenzyl bromideHCID 954258—
반응물Tert-butyl 2-(2,3-dichloro-4-(3-hydroxy-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoateHCID 25062865—
생성물Tert-butyl 2-(4-(3-(4-iodobenzyloxy)-3-(5-(4-(trifluoromethyl) phenyl)thien-2-yl)propyl)-2,3-dichlorophenoxy)-2-methylpropanoateHCID 25062867—

반응 단계

Tert-butyl 2-(4-(3-(4-iodobenzyloxy)-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)-2,3-dichlorophenoxy)-2-methylpropanoate is prepared from tert-butyl 2-(2,3-dichloro-4-(3-hydroxy-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoate using 1.1 equivalents of sodium hydride and 1.1 equivalents of 4-iodobenzyl bromide according to general procedure H.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08088819B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-8c65d6f7a55b463b87fa5e56217b0ff8
출처 메모uspto-grants-2012_01