2-Fluorophenol → 5-Chloro-2-(2-fluoro-phenoxy)-3-nitro-pyridine
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Br[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([Cl:11])=[CH:4][N:3]=1.[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[OH:19].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[Cl:11][C:5]1[CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]([O:19][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[F:12])=[N:3][CH:4]=1참가 물질
5
실험 절차
This compound was prepared according to general procedure A using 2-bromo-5-chloro-3-nitro-pyridine (750 mg, 3.17 mmol), 2-fluorophenol (463 mmol, 4.13 mmol), K2CO3 (437 mg, 4.75 mmol) and DMF (5 mL). MS m/z: 269.0 (M+H).
후처리
- customThis compound was prepared
출처 및 근거
- ORD 기록
- ord-b2956102dccc421ba3ab76c4dda45bae
- 출처 데이터셋
- uspto-grants-2012_01
- 특허 번호
- US08093247B2
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