Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tert-butyl 4-[2-(4-methanesulfonyl-phenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate → 2-[4-[2-(4-Methanesulfonylphenoxymethyl)pyridin-5-yl]piperidin-1-yl]-5-pentylpyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tert-butyl 4-[2-(4-methanesulfonyl-phenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate | HCID 44819975 | — |
| 반응물 | HCID 86654266 | HCID 86654266 | — |
| 생성물 | 2-[4-[2-(4-Methanesulfonylphenoxymethyl)pyridin-5-yl]piperidin-1-yl]-5-pentylpyrimidine | HCID 67083133 | — |
반응 단계
The title compound was prepared from tert-butyl 4-[2-(4-methanesulfonylphenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate (Example 1) (50 mg, 0.11 mmol) and 5-pentyl-2-bromopyrimidine (37 μL, 0.22 mmol) following a procedure analogous to that in Example 48 as a white crystal (35 mg, yield 64%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536176B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-e8436764dc3747dababb18eb91fd24a0 |
| 출처 메모 | uspto-grants-2013_09 |