돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 421678생성일: 2026년 10월 27일

4-(4-Methylpiperazin-1-yl)benzoic acid → N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

https://huagongshe.com/reaction/421678

반응식

참여 물질

역할이름HCID투입량
반응물4-(4-Methylpiperazin-1-yl)benzoic acidHCID 736532—
반응물N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamideHCID 16730560—
생성물N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamideHCID 16730714—

반응 단계

N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (0.15 mmol) was used in general procedure 2 with 4-(4-methylpiperazin-1-yl)benzoic acid (0.167 mmol). The product was purified by RP-HPLC to give N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide. MS (Q1) 532.0 (M)+

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08101610B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-a3bfcaa7085843a3bb302caec3b4a782
출처 메모uspto-grants-2012_01