Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(3-Amino-1,2,4-oxadiazol-5-yl)-1-azabicyclo(2.2.1)heptane → HCID 86086918, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(3-Amino-1,2,4-oxadiazol-5-yl)-1-azabicyclo(2.2.1)heptane | HCID 163938 | — |
| 반응물 | 3-Chloro-n'-hydroxy-2-methylbenzidine | HCID 87101445 | — |
| 생성물 | HCID 86086918 | HCID 86086918 | 46% |
반응 단계
According to the general protocol for oxadiazole synthesis described in Example 40(C) the conversion of 3-chloro-N′-hydroxy-2-methylbenzidine (628 mg, 3.4 mmol) afforded 387 mg of 5-(but-3-ynyl)-3-(3-chloro-2-methylphenyl)-1,2,4-oxadiazole (Yield: 46%) as yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08101637B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-4feea008220d476d99fb328136536254 |
| 출처 메모 | uspto-grants-2012_01 |