Hydrochloric Acid → HCID 54298459, 화합물
반응식
[CH3:1][O:2][C:3](=[O:17])[C:4]1[CH:9]=[C:8]([CH3:10])[C:7]([O:11]COC)=[C:6]([O:15][CH3:16])[CH:5]=1.Cl>C1COCC1.C(OCC)(=O)C>[CH3:1][O:2][C:3](=[O:17])[C:4]1[CH:9]=[C:8]([CH3:10])[C:7]([OH:11])=[C:6]([O:15][CH3:16])[CH:5]=1참가 물질
5
실험 절차
To a solution of 3-methoxy-4-methoxymethoxy-5-methylbenzoic acid methyl ester (650 mg) in THF (5 mL) was added 6N-hydrochloric acid (5 mL), and the mixture was stirred at room temperature for 1 hour. The reaction solution was diluted with ethyl acetate, washed with water and saturated brine, dried over anhydrous sodium sulfate, and concentrated in vacuo. The residue was purified by column chromatography on silica gel (hexane:ethyl acetate=4:1, v/v) to give the title compound (365 mg).
후처리
- washwashed with water and saturated brine
- dry with materialdried over anhydrous sodium sulfate
- concentrationconcentrated in vacuo
- customThe residue was purified by column chromatography on silica gel (hexane
출처 및 근거
- ORD 기록
- ord-6aba6d8b2a5946dea3097d1ac2bab144
- 출처 데이터셋
- uspto-grants-2012_01
- 특허 번호
- US08101774B2
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