Piperidine → 1-Piperidinesulfonamide

HRID 424687

반응식

HRID 424687 반응식
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:7](N)([NH2:10])(=[O:9])=[O:8]>O1CCOCC1>[N:1]1([S:7]([NH2:10])(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 8082PiperidineHCID 82267Sulfamide

생성물 1

HCID 2767411-Piperidinesulfonamide

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

Piperidine (3.0 g) and sulfamide (5.93 g) in 1,4-dioxane (100 ml) were heated at reflux for 24 h. The solvent was evaporated under reduced pressure and the resulting solid suspended in CHCl3. The suspension was filtered and the filtrate concentrated in vacuo to afford the subtitle compound as a white solid. Yield: 3.85 g.

후처리

  1. temperatureat reflux for 24 h
  2. customThe solvent was evaporated under reduced pressure
  3. filtrationThe suspension was filtered
  4. concentrationthe filtrate concentrated in vacuo

출처 및 근거

ORD 기록
ord-ee0d5e1762a847a1929db3d27db38938
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08106063B2

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