Acetic Anhydride → HCID 22403906, 화합물

반응식

[NH2:1][C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:18])[CH:8]=2)[N:3]=1.[C:19](OC(=O)C)(=[O:21])[CH3:20]>>[C:19]([NH:1][C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:18])[CH:8]=2)[N:3]=1)(=[O:21])[CH3:20]

참가 물질

반응물 2

HCID 7918Acetic Anhydride

HCID 672273HCID 672273, 화합물

생성물 1

HCID 22403906HCID 22403906, 화합물

반응 조건

온도: 70 °C

실험 절차

A mixture of 0.1 g of 2-amino-6-chloro-4-phenylquinoline and 8 ml of acetic anhydride was stirred at 70° C. for 1 hour, the solvent was removed by distillation, the solid residue was stirred with water, and the crystalline substance was filtered off.

후처리

customthe solvent was removed by distillation
stirringthe solid residue was stirred with water
filtrationthe crystalline substance was filtered off

출처 및 근거

ORD 기록: ord-cccb3e67d18d4380b9c159108951512a
출처 데이터셋: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08106204B2

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