1-Bromopentane → 7-fluoro-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione

HRID 425579

반응식

HRID 425579 반응식
BrC1C=CC=C2C=1C=CN2.[F:11][C:12]1[CH:13]=[CH:14][CH:15]=[C:16]2[C:20]=1[NH:19][C:18](=[O:21])[C:17]2=[O:22].BrCCCCC.Br[CH2:30][C:31]1[O:32][C:33]([C:36]([F:39])([F:38])[F:37])=[CH:34][CH:35]=1>>[F:11][C:12]1[CH:13]=[CH:14][CH:15]=[C:16]2[C:20]=1[N:19]([CH2:30][C:31]1[O:32][C:33]([C:36]([F:39])([F:38])[F:37])=[CH:34][CH:35]=1)[C:18](=[O:21])[C:17]2=[O:22]

참가 물질

5

실험 절차

Following the procedure as described in PREPARATION 1A, and making tnon-critical variations to replace 4-bromoindole with 7-fluoroisatin, and 1-bromopentane with 2-(bromomethyl)-5-(trifluoromethyl)furan, the title compound was obtained (34%): MS (ES+) m/z 336.2 (M+23).

출처 및 근거

ORD 기록
ord-eeccaab0de1f4b48bffcc4d0c1e23b03
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08106087B2

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