1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → 4,6-Diphenyl-2-(2-phthalimidoethyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine
반응식
[C:1]1([C:7]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=3)=[C:11]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[N:10]=[C:9]3[NH:25][N:26]=[CH:27][C:8]=23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[CH2:29][CH2:30][N:31]1[C:35](=[O:36])[C:34]2=[CH:37][CH:38]=[CH:39][CH:40]=[C:33]2[C:32]1=[O:41]>>[C:1]1([C:7]2[C:8]3[C:9](=[N:25][N:26]([CH2:29][CH2:30][N:31]4[C:35](=[O:36])[C:34]5=[CH:37][CH:38]=[CH:39][CH:40]=[C:33]5[C:32]4=[O:41])[CH:27]=3)[N:10]=[C:11]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:12]=2[C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
3
실험 절차
Following a similar procedure to that described in examples 6 and 7, but using 4,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 2) instead of 4,6-bis(4-fluorophenyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine and N-(2-bromoethyl)phthalimide instead of iodoethane, the title compound was obtained (yield: 31%).
출처 및 근거
- ORD 기록
- ord-04e337fc91c94a5184a2716db9c83c69
- 출처 데이터셋