Diisopropylethylamine → N-[(2S)-4-{3-[4-(Azetidin-1-ylcarbonyl)piperidin-1-yl]azetidin-1-yl}-2-(4-fluorophenyl)butyl]-3-bromo-N-methyl-5-(trifluoromethyl)benzamide

반응식

[Br:1][C:2]1[CH:3]=[C:4]([CH:21]=[C:22]([C:24]([F:27])([F:26])[F:25])[CH:23]=1)[C:5]([N:7]([CH2:9][C@H:10]([C:14]1[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=1)[CH2:11][CH:12]=O)[CH3:8])=[O:6].[NH:28]1[CH2:31][CH:30]([N:32]2[CH2:37][CH2:36][CH:35]([C:38]([N:40]3[CH2:43][CH2:42][CH2:41]3)=[O:39])[CH2:34][CH2:33]2)[CH2:29]1.CCN(C(C)C)C(C)C.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>C(Cl)Cl.CO>[N:40]1([C:38]([CH:35]2[CH2:36][CH2:37][N:32]([CH:30]3[CH2:29][N:28]([CH2:12][CH2:11][C@@H:10]([C:14]4[CH:15]=[CH:16][C:17]([F:20])=[CH:18][CH:19]=4)[CH2:9][N:7]([CH3:8])[C:5](=[O:6])[C:4]4[CH:21]=[C:22]([C:24]([F:26])([F:27])[F:25])[CH:23]=[C:2]([Br:1])[CH:3]=4)[CH2:31]3)[CH2:33][CH2:34]2)=[O:39])[CH2:41][CH2:42][CH2:43]1