Fenteracol → 2-(2,4,5-Trichloro-phenoxy)-ethyl 2-[4-(4-chlorophenoxymethyl)-phenoxy]-propionate

HRID 426438

반응식

HRID 426438 반응식
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([O:6][CH2:7][C:8]2[CH:20]=[CH:19][C:11]([O:12][CH:13]([CH3:18])[C:14]([O:16][CH3:17])=[O:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[Cl:23][C:24]1[CH:33]=[C:32]([Cl:34])[C:31]([Cl:35])=[CH:30][C:25]=1[O:26][CH2:27]CO.[Na]>CC(C)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][CH2:7][C:8]2[CH:20]=[CH:19][C:11]([O:12][CH:13]([CH3:18])[C:14]([O:16][CH2:17][CH2:27][O:26][C:25]3[CH:30]=[C:31]([Cl:35])[C:32]([Cl:34])=[CH:33][C:24]=3[Cl:23])=[O:15])=[CH:10][CH:9]=2)=[CH:21][CH:22]=1

참가 물질

5

반응물 3

HCID 16462FenteracolHCID 5360545SodiumHCID 19834514Methyl 2-[4-(4-Chlorophenoxy-methyl)-phenoxy]-propionate

생성물 1

HCID 538539382-(2,4,5-Trichloro-phenoxy)-ethyl 2-[4-(4-chlorophenoxymethyl)-phenoxy]-propionate

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A mixture consisting of 2.2 gm of methyl 2-[4-(4-chlorophenoxy-methyl)-phenoxy]-propionate, 2.4 gm of 2-(2,4,5-trichloro-phenoxy)-ethanol and 0.03 gm of sodium was heated at about 120°-150° C. and a pressure of 150 mm Hg for four hours. After cooling, the reaction mixture was briefly boiled with acetone, the cooled solution was filtered, and the solvent was removed from the filtrate in vacuo. The residue was recrystallized from ethanol/water, yielding 1.3 gm (36% of theory) of the compound of the formula ##STR19## which had a melting point of 83° C.

후처리

  1. temperaturewas heated at about 120°-150° C.
  2. temperatureAfter cooling
  3. filtrationthe cooled solution was filtered
  4. customthe solvent was removed from the filtrate in vacuo
  5. customThe residue was recrystallized from ethanol/water
  6. customyielding 1.3 gm (36% of theory) of the compound of the formula ##STR19## which

출처 및 근거

ORD 기록
ord-fac85202ceaa4c29acd8b6831978d813
출처 데이터셋
uspto-grants-1979_10
특허 번호
US04169720

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