Sodium borohydride → (2-Isopropyl-6-methylphenyl)methanol
반응식
[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH:6]=[O:7])([CH3:3])[CH3:2].[BH4-].[Na+]>CO>[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6][OH:7])([CH3:3])[CH3:2]참가 물질
4
실험 절차
To a solution of 2-isopropyl-6-methylbenzaldehyd (1.75 g, 10.8 mmol) in methanol (15 ml) was added sodium borohydride (0.35 g, 9.5 mmol) and the mixture was stirred 1 h. at room temperature. The solvent was evaporated under reduced pressure and to the residue was added hexane and water. The organic layer was separated and evaporated under reduced pressure to give 1.73 g (98%) of the title compound as an oil.
후처리
- customThe solvent was evaporated under reduced pressure and to the residue
- additionwas added hexane and water
- customThe organic layer was separated
- customevaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-e446b94faa7448ce83e2e8534874030c
- 출처 데이터셋
- uspto-grants-2001_11
- 특허 번호
- US06313137B1
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